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Research & Education

GLP-3 RT Side Effects: A Review of Adverse Events Reported in Published Research

Quick answer: in the published Phase 2 trial of retatrutide (GLP-3 RT), the most common adverse events were gastrointestinal: nausea, diarrhea, vomiting, and constipation. They were dose-related, mostly mild to moderate, and clustered during dose escalation. A dose-dependent increase in heart rate was also reported, peaking early and declining over the study.

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